Une soucoupe volante en panne atterrit dans le desert d'Arizona. Les extraterrestres, globes oculaires geants, prennent l'apparence des etres humains qu'ils hypnotisent.

Julie, an American on vacation in Mexico, spots a giant, one-eyed amoeba rising from the ocean, but when she tries to tell the authorities, no one believes her. She finally teams up with a marine biologist in an attempt to destroy it.